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However, in Voon et al. During reward outcome, individuals with substance addiction showed increased activation in the ventral striatum, whereas individuals with gambling addiction showed decreased activation in the dorsal striatum compared with healthy control individuals. Therefore, we would first like to discuss the available results, then propose their interpretations in the context of IST and RDS theories. Gray matter deficits and altered resting-state connectivity in the superior temporal gyrus among individuals with problematic hypersexual behavior. Ventral striatum and ventral pallidum:

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RDS predicts hypoactivation for rewarding stimuli and for cues predicting such stimuli in between group comparison.

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It is important to note that all of the studies included in this meta-analysis were using monetary incentives; therefore, described patterns of reactivity for cues and rewards were non-specific for certain substance related addictions. Szczypinski JJ, Gola M. But one very important question emerges: Studies on substance and gambling addiction show that learned conditional stimuli so called cues related to addiction evoke increased responses in the ventral striatum as well as increased motivated behavior manifested with shorter reaction times among addicted individuals, while responses to the reward itself remain unchanged or undergo blunting over time 26 If one assumes that an erotic picture or video plays the role of cue, then increased ventral striatal reactivity among subjects with CSB in comparison with controls would speak in favor of the addiction hypothesis. World Psychiatry

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